Hong Kong Journal of Dermatology and Venereology

Volume 18 Number 2, Summer 2010
Abstract

Paradoxical pustular psoriasis flare after infliximab therapy
抗腫瘤壞死因子誘發反常式牛皮癬復發的病例

YY Leung 梁盈盈 and KM Ho 何景文

While tumour necrosis factor (TNF)-α blockers have proven efficacy for the treatment of both arthritis and psoriasis, new appearance or exacerbation of psoriasis after TNF-α blockers has been increasingly reported. We report the first local case of psoriasis flare after infliximab treatment and review the literature on the topic.

抗腫瘤壞死因子對牛皮癬及牛皮癬關節炎的療效顯著,但抗腫瘤壞死因子誘發反常式牛皮癬復發或新發病案例卻時有報告。我們現報告一本地首例,並檢討報導相關的醫學文獻以作參考。

Keywords : Adverse event, psoriatic arthritis, psoriasis flare, tumour necrosis factor-a blockers

關鍵詞:不良事件,牛皮癬關節炎,牛皮癬復發,抗腫瘤壞死因子